Impact of a history of metastases or synchronous metastases on survival in patients with locally recurrent rectal cancer

Aim Patients with locally recurrent rectal cancer (LRRC) frequently present either synchronous metastases or a history of metastases. This study was conducted to evaluate whether LRRC patients without have different oncological outcome compared treated curative intent potentially curable Method All consecutive who underwent intentionally surgery between 2005 and 2017 in large tertiary hospital were retrospectively reviewed categorized as having no metastases, (curatively treated) unresectable distant excluded from the analysis. Results Of 349 analysed, 261 (75%) had 42 (12%) 46 (13%) The 3-year metastasis-free survival 52%, 33% 13% respectively (P < 0.001) A did not influence overall (OS), but there trend towards worse OS (hazard ratio 1.43; 95% CI 0.98–2.11). Conclusion curatively an comparable that should therefore be intent. However, poor OS; these patients, individualized treatment approach observe behaviour disease is recommended.